|
Symbol Name ID |
Stx1a
syntaxin 1A (brain) MGI:109355 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased CSF protein concentration |
Aganglionic megacolon |
Extrapyramidal muscular rigidity |
Abnormal cerebellum morphology |
Gait ataxia |
Myoclonus |
Hemiparesis |
Aphasia |
Depression |
Irritability |
Delusion |
Anxiety |
Hallucinations |
Apathy |
Personality changes |
Confusion |
Memory impairment |
Dementia |
Intellectual disability |
| Disease(s) Associated with STX1A | |||||||||||||||||||
| Creutzfeldt-Jakob disease | |||||||||||||||||||
| Hirschsprung's disease |
| Mouse Phenotypes | nervous system phenotype |
abnormal synaptic vesicle number |
abnormal nervous system physiology |
abnormal hypothalamus secretion |
abnormal neuron physiology |
abnormal synaptic vesicle recycling |
impaired synaptic plasticity |
abnormal excitatory postsynaptic potential |
reduced long-term potentiation |
increased post-tetanic potentiation |
decreased synaptic depression |
enhanced paired-pulse facilitation |
|
| Availability | Mouse Genotype | ||||||||||||
| Stx1atm1Tfuj/Stx1atm1Tfuj | |||||||||||||
| Stx1atm1Migar/Stx1a+ | * | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools